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Feeding problems and gastrointestinal diseases in Down syndrome.
This study lists the various anomalies on the basis of 504 references selected from a PubMed search in October 2018.
RESULTS: The anomalies are grouped into three categories: anatomical anomalies: duodenal atresia and stenosis (3.9%), duodenal web and annular pancreas; aberrant right subclavian artery (12% of children with DS with cardiac anomaly); Hirschsprung's disease (2.76%); anorectal malformation (1.16%); congenital vascular malformations of the liver; orofacial cleft, bifid uvula (4.63%), and submucous orofacial cleft; esophageal atresia (0.5-0.9%); pyloric stenosis (0.3%); diaphragmatic hernia; malrotation of ...
Source: Archives de Pediatrie - November 25, 2019 Category: Pediatrics Authors: Ravel A, Mircher C, Rebillat AS, Cieuta-Walti C, Megarbane A Tags: Arch Pediatr Source Type: research
Gene variants as risk factors for gastroschisis
In a population‐based case‐control study in California of 228 infants, we investigated 75 genetic variants in 20 genes and risk of gastroschisis with regard to maternal age, race/ethnicity, vitamin use, and smoking exposure. We hypothesized that genes related to vascular compromise may interact with environmental factors to affect the risk of gastroschisis. Haplotypes were constructed for 75 gene variants using the HaploView program. Risk for gastroschisis associated with each gene variant was calculated for both the homozygotes and the heterozygotes, with the homozygous wildtypes as the referent. Risks were estimated ...
Source: American Journal of Medical Genetics Part A - September 11, 2016 Category: Genetics & Stem Cells Authors: Amy M. Padula, Wei Yang, Kathleen Schultz, Lauren Tom, Bin Lin, Suzan L. Carmichael, Edward J. Lammer, Gary M. Shaw Tags: Original Article Source Type: research
Standardised parenteral nutrition provision in neonates managed postoperatively for gastroschisis
Conclusion
Standardised parenteral nutrition provision in neonates managed postoperatively for gastroschisis is a promising safe option and does not seem to adversely affect monitored parameters any more than individualised TPN.
Source: Archives of Disease in Childhood - May 18, 2015 Category: Pediatrics Authors: Windscheif, P.-M., Welsh, R., Lakhoo, K., Rivlin, G., McCormick, K. Tags: Posters Source Type: research
Gastroschisis in a fetus with a congenital neuroblastoma: Association or coincidence?
ConclusionWe cannot rule out the possibility that a clotting defect, commonly observed in disseminated malignancies such as a metastatic neuroblastoma may be associated with the etiology of the gastroschisis, as this defect may result from a thrombosis occurring around 3 to 4 weeks of gestation, a period when neuroblasts development occurs into the adrenal medulla. However, we cannot exclude the possibility that both events may have occurred simultaneously by chance. Birth Defects Research (Part A), 2016. © 2016 Wiley Periodicals, Inc.
Source: Birth Defects Research Part A: Clinical and Molecular Teratology - February 1, 2016 Category: Perinatology & Neonatology Authors: Rafael F.M. Rosa, Laura Michelon, Átila Masiero, Adyr E.V. Faria, Vanessa F. De Souza, Cristine Dietrich, Luciano V. Targa, Valentina O. Provenzi, Silvana R.S. Pires, Paulo R.G. Zen Tags: Research Article Source Type: research
The Search for the Elusive Elixir of Life
By TOM EMERICK
Here’s the executive summary: Most disease and health spending is age-related. As we age we get infirmities ranging from dementia to cancer to vascular disease. Nothing can prevent aging. Period. For millennia mankind has been been on a futile search to prevent aging.
Search for the Elusive Elixir of Life
For 3500 or more years mankind has been searching for the mythological Elixir of Life, the fountain of youth, the philosophers stone, pool of nectar, etc, that will defeat aging and extend life, if not achieve immortality.
According to Wiki, “The elixir of life, also known as the elixir of immortality a...
Source: The Health Care Blog - February 4, 2016 Category: Consumer Health News Authors: Simon Nath Tags: THCB Tom Emerick Source Type: blogs
Evidence From Web-Based Dietary Search Patterns to the Role of B12 Deficiency in Non-Specific Chronic Pain: A Large-Scale Observational Study
Conclusions: Our findings show that Internet search patterns are a useful way of investigating health questions in large populations, and suggest that low B12 intake may be associated with a broader spectrum of neurological disorders than previously thought.
Source: Journal of Medical Internet Research - January 5, 2018 Category: General Medicine Authors: Eitan Giat Elad Yom-Tov Source Type: research
Nutritional Factors and Preservation of C-Peptide in Youth With Recently Diagnosed Type 1 Diabetes: SEARCH Nutrition Ancillary Study.
CONCLUSIONS Increased intake of branched-chain amino acids and long-chain omega-3 fatty acids may support preservation of β-cell function. This represents a new direction for research to improve prognosis for type 1 diabetes.
PMID: 23801797 [PubMed - in process]
Source: Diabetes Care - July 1, 2013 Category: Endocrinology Authors: Mayer-Davis EJ, Dabelea D, Crandell JL, Crume T, D'Agostino RB, Dolan L, King IB, Lawrence JM, Norris JM, Pihoker C, The N Tags: Diabetes Care Source Type: research
Serum biochemical, blood gas and antioxidant status in search and rescue dogs before and after simulated fieldwork
Publication date: Available online 6 July 2015 Source:The Veterinary Journal Author(s): J.W. Spoo , D.L. Zoran , R.L. Downey , K. Bischoff , J.J. Wakshlag The aim of the study was to assess the physiological and antioxidant status before and after a 4 h search and rescue field exercise, with handlers, under warm-weather conditions performing activities compared to a control group of similarly trained dogs at rest. Serum chemistry demonstrated a decrease in serum sodium (Na) and potassium (K) in both exercising and control groups, however only Na was decreased significantly (P < 0.05) after exercise and hematocrits...
Source: The Veterinary Journal - July 7, 2015 Category: Veterinary Research Source Type: research
Health economic analyses of psoriasis management: a systematic literature search
The objective was to identify health economic evaluations of psoriasis treatments that have been published to date. Of particular interest were the mostly used analysis and outcome parameters, the compared treatments, and the question, if available health economic studies may be used to perform a meta-analysis of qualitative findings. A systematic literature search using PubMed Medline, Ovid Medline, and Cochrane Library was performed for articles, published and available until mid of January 2016. Among the key words were the terms “psoriasis” and “cost-effectiveness”. The search resulted in 318 articles without d...
Source: Archives of Dermatological Research - July 18, 2016 Category: Dermatology Source Type: research
Relationship between serum 25-hydroxyvitamin D and parathyroid hormone in the search for a biochemical definition of vitamin D deficiency in children.
Conclusions:Vitamin D deficiency, based on PTH elevation, was best defined by a 25OHD level of < 34 nmol/l. Since deficient calcium supply often co-exists with vitamin D deficiency and both can independently cause nutritional rickets, a threshold for the skeletal effects of vitamin D should not be based purely on 25OHD levels.Pediatric Research (2013); doi:10.1038/pr.2013.139.
PMID: 23999068 [PubMed - as supplied by publisher]
Source: Pediatric Research - September 2, 2013 Category: Pediatrics Authors: Atapattu N, Shaw N, Högler W Tags: Pediatr Res Source Type: research
Title: In Search of “Just Right”: The Challenge of Regulating Arsenic in Rice
Charles W. Schmidt, MS, an award-winning science writer from Portland, ME, has written for Discover Magazine, Science, and Nature Medicine.
Background image: © Koji Kitagawa/amanaimages/Corbis
About This Article open
Citation: Schmidt CW. 2015. In search of “just right”: the challenge of regulating arsenic in rice. Environ Health Perspect 123:A16–A19; http://dx.doi.org/10.1289/ehp.123-A16
News Topics: Agriculture and Farming, Arsenic, Diet and Nutrition, Drinking Water Quality, Food Safety and Regulation, Laws, Regulations, and Policy, Risk Assessment, Soil Pollution, Standards
Published: 1 January 2015
PDF Ver...
Source: EHP Research - December 31, 2014 Category: Environmental Health Authors: Web Admin Tags: Featured News Spheres of Influence Agriculture and Farming Arsenic Diet and Nutrition Drinking Water Quality Food Safety and Regulation Risk Assessment Soil Pollution Standards Source Type: research
Longitudinal associations of nutritional factors with glycated hemoglobin in youth with type 1 diabetes: the SEARCH Nutrition Ancillary Study.
CONCLUSIONS: Several nutritional factors may be associated with Hb A1c during early stages of disease progression in youth recently diagnosed with T1D. In addition to the overall role of major macronutrients such as carbohydrates and protein, leucine and n-3 fatty acid intakes, such as of EPA, may be important for long-term glycemic control.
PMID: 25948670 [PubMed - as supplied by publisher]
Source: The American Journal of Clinical Nutrition - May 6, 2015 Category: Nutrition Authors: Lamichhane AP, Crandell JL, Jaacks LM, Couch SC, Lawrence JM, Mayer-Davis EJ Tags: Am J Clin Nutr Source Type: research
Have we Been Hooked on Micronutrients in our Search for the Solution to Stunting?
Co-author Richard D. Semba, Johns Hopkins University
Today, some 160 million children under five years of age don't get the food and nutrients that their bodies need for optimal growth and development. One hundred and sixty million children that are likely to remain trapped in a vicious cycle of malnutrition and poverty. No wonder the 'new' Sustainable Development Goals (SDGs) have 'no poverty' and 'zero hunger' as the first and second of the 17 Global Goals. This makes the eradication of malnutrition, with a special focus on children, a top priority for countries as they turn the SDGs into actions.
To support the SDGs,...
Source: Science - The Huffington Post - April 1, 2016 Category: Science Source Type: news
Serum 25-Hydroxyvitamin D Insufficiency in Search of a Bone Disease.
Conclusion: At a threshold of 25(OH)D of 30 nmol/L or below, abnormalities in biochemical features are supportive of the notion of a 'deficiency' state predisposing to bone disease. However, no deleterious effects are found in subjects within an 'insufficient' threshold of 25(OH)D of 30 to 75 nmol/L which challenges the rationale in using supplementation of these individuals.
PMID: 28379394 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - March 30, 2017 Category: Endocrinology Authors: Shah S, Chiang C, Sikaris K, Lu Z, Bui M, Zebaze R, Seeman E Tags: J Clin Endocrinol Metab Source Type: research
